Cardene

Definition

Cardene (nicardipine) is a calcium channel blocker used to treat high blood pressure and angina. It works by relaxing blood vessels so the heart doesn't have to pump as hard.

5 Must Know Facts For Your Next Test

1. Cardene specifically targets L-type calcium channels in vascular smooth muscle.
2. It is often used in cases of hypertensive crisis due to its rapid onset of action when administered intravenously.
3. Common side effects include headache, dizziness, and flushing due to vasodilation.
4. Cardene can interact with other antihypertensive medications, leading to an additive effect in lowering blood pressure.
5. Patients with severe aortic stenosis should avoid Cardene as it can exacerbate this condition.

Review Questions

• What specific type of calcium channel does Cardene target?
• Why might Cardene be chosen for treating a hypertensive crisis?
• List three common side effects associated with Cardene.

Related terms

Amlodipine:

Another calcium channel blocker used for treating hypertension and angina.

Nifedipine:

Calcium channel blocker similar to nicardipine but more commonly used for chronic management of hypertension and angina.

Verapamil:

A calcium channel blocker that also affects the heart's conduction system, often used for arrhythmias.