Verapamil

Definition

Verapamil is a calcium channel blocker used to treat hypertension, angina, and certain types of cardiac dysrhythmias. It works by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, thereby reducing heart rate and dilating blood vessels.

5 Must Know Facts For Your Next Test

1. Verapamil is classified as a Class IV antidysrhythmic drug.
2. It is commonly prescribed for conditions such as atrial fibrillation and supraventricular tachycardia.
3. Verapamil can cause side effects like hypotension, bradycardia, and constipation.
4. The drug inhibits L-type calcium channels in both the myocardium and vascular smooth muscle.
5. Patients taking Verapamil should avoid grapefruit juice as it can increase the drug's plasma concentration.

Review Questions

• What class of antidysrhythmic drugs does Verapamil belong to?
• Name two cardiovascular conditions that Verapamil is commonly used to treat.
• What are some common side effects associated with Verapamil?

Related terms

Calcium Channel Blockers:

A group of medications that inhibit the entry of calcium ions into heart and blood vessel walls.

Antidysrhythmic Drugs:

Medications used to treat abnormal heart rhythms.

Hypertension:

A chronic medical condition characterized by elevated blood pressure.