Bivalirudin
from class:
Pharmacology for Nurses
Definition
Bivalirudin is a direct thrombin inhibitor used as an anticoagulant. It is often employed in patients undergoing percutaneous coronary intervention (PCI).
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5 Must Know Facts For Your Next Test
- Bivalirudin is administered intravenously.
- It works by directly inhibiting both free and clot-bound thrombin.
- Commonly used in patients with heparin-induced thrombocytopenia (HIT).
- Has a rapid onset of action and short half-life, allowing for quick adjustments.
- Requires monitoring of activated clotting time (ACT) during procedures.
Review Questions
- How does bivalirudin inhibit thrombin?
- Why might bivalirudin be preferred over heparin in certain patients?
- What is the significance of bivalirudin's short half-life in clinical practice?
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