Aldactone

Definition

Aldactone, also known as spironolactone, is a potassium-sparing diuretic used to treat conditions such as hypertension and heart failure. It works by inhibiting the effects of aldosterone in the kidneys, promoting sodium excretion while retaining potassium.

5 Must Know Facts For Your Next Test

1. Aldactone is classified as a potassium-sparing diuretic, preventing the loss of potassium when used.
2. It is commonly prescribed for patients with congestive heart failure to reduce fluid retention and improve symptoms.
3. Spironolactone can be used in combination with other diuretics to enhance therapeutic effects while minimizing potassium loss.
4. Common side effects include hyperkalemia (elevated potassium levels), gynecomastia (breast enlargement in men), and gastrointestinal disturbances.
5. Aldactone also has anti-androgenic properties, making it useful for treating conditions like hirsutism (excessive hair growth) and acne.

Review Questions

• What class of diuretics does Aldactone belong to?
• What are some common side effects associated with Aldactone?
• How does Aldactone's mechanism of action help in treating heart failure?

Related terms

Thiazide Diuretics: A class of diuretics that inhibit sodium reabsorption in the distal convoluted tubule.

Loop Diuretics: Diuretics that act on the ascending loop of Henle in the kidney to inhibit sodium and chloride reabsorption.

Angiotensin-Converting Enzyme (ACE) Inhibitors: Medications that inhibit the conversion of angiotensin I to angiotensin II, reducing blood pressure and decreasing workload on the heart.