Syn periplanar

Definition

Syn periplanar refers to the spatial arrangement in which atoms or groups involved in a chemical reaction, specifically in an E2 elimination reaction, are on the same side and in the same plane. This arrangement is crucial for the reaction to proceed efficiently as it allows for the optimal overlap of orbitals required for the formation and breaking of bonds.

Related terms

E2 Reaction: A bimolecular elimination reaction where a proton is removed from one carbon atom while a leaving group is expelled from an adjacent carbon, resulting in the formation of a double bond.

Leaving Group: A substituent that can depart with an electron pair, making it crucial for nucleophilic substitution and elimination reactions.

Deuterium Isotope Effect: The effect observed on the rate of chemical reactions when a hydrogen atom is replaced by deuterium, often used to investigate reaction mechanisms