Stork enamine reaction

Definition

The Stork enamine reaction is a chemical reaction involving the alkylation of an aldehyde or ketone using an enamine as the nucleophile, followed by hydrolysis to produce a substituted ketone or aldehyde. This process allows for the synthesis of complex carbonyl compounds from simpler ones without overreaction issues.

Related terms

Enamines: Compounds formed by the reaction of a secondary amine with an aldehyde or ketone, characterized by a double bond between carbon and nitrogen.

Alkylation: A chemical process that introduces an alkyl group into a molecule, often increasing its complexity or changing its reactivity.

Carbonyl Condensation Reactions: A class of reactions where two carbonyl-containing molecules combine to form a larger molecule, often involving dehydration (loss of water) as part of the process