Cahn–Ingold–Prelog sequence rules

Definition

The Cahn-Ingold-Prelog (CIP) sequence rules are a set of guidelines used to systematically name the spatial arrangement of atoms around a stereocenter, helping to determine the configuration of molecules in organic chemistry. These rules prioritize atoms or groups attached to a chiral center based on atomic number, isotopic mass, and connectivity, facilitating the assignment of R (rectus) or S (sinister) configurations.

Related terms

Chiral Center: A carbon atom bonded to four different groups or atoms, creating non-superimposable mirror images.

Stereochemistry: The study of how the spatial arrangement of atoms in molecules affects their chemical properties and reactions.

Enantiomers: Molecules that are mirror images of each other but cannot be superimposed on one another, much like left and right hands