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Butyryl

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Organic Chemistry

Definition

Butyryl is a functional group derived from the carboxylic acid butyric acid. It is a four-carbon acyl group that can be found in various organic compounds, particularly in the context of carboxylic acids and nitriles.

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5 Must Know Facts For Your Next Test

  1. The butyryl group is named after the carboxylic acid butyric acid, which has a four-carbon chain.
  2. Butyryl-containing compounds are often found in biological systems, such as in the form of butyryl-CoA, an important intermediate in fatty acid metabolism.
  3. In the context of carboxylic acids, the butyryl group can be used to name derivatives of butyric acid, such as butyryl chloride or butyryl anhydride.
  4. When a butyryl group is attached to a nitrile, it forms a butyronitrile, which is a type of aliphatic nitrile used in various industrial applications.
  5. The presence of the butyryl group can significantly influence the physical and chemical properties of the resulting compound, such as its solubility, reactivity, and biological activity.

Review Questions

  • Explain the relationship between the butyryl group and the carboxylic acid butyric acid.
    • The butyryl group is derived from the four-carbon carboxylic acid, butyric acid. It is an acyl group with the formula CH3CH2CH2C(=O)-, which can be attached to various organic compounds, such as in the formation of butyryl-containing esters, amides, or nitriles. The butyryl group retains the four-carbon chain structure of butyric acid and is often used to name derivatives or functional group substitutions involving the original carboxylic acid.
  • Describe how the butyryl group can be incorporated into nitrile compounds and the significance of this structural feature.
    • When a butyryl group is attached to a nitrile functional group, it forms a butyronitrile, which is a type of aliphatic nitrile. The presence of the butyryl group in a nitrile compound can influence its physical and chemical properties, such as its solubility, reactivity, and potential biological activities. Butyronitriles are used in various industrial applications, and the incorporation of the butyryl group can be an important structural feature in the synthesis and modification of nitrile-containing organic compounds.
  • Analyze the role of the butyryl group in biological systems, particularly in the context of fatty acid metabolism.
    • In biological systems, the butyryl group is often found in the form of butyryl-CoA, which is an important intermediate in the β-oxidation pathway of fatty acid metabolism. Butyryl-CoA is produced during the breakdown of butyric acid, a short-chain fatty acid commonly found in butter and other dairy products. The presence of the butyryl group in this metabolic intermediate allows for its further conversion and utilization in energy-producing pathways, highlighting the significance of the butyryl group in the overall regulation and efficiency of cellular metabolism.

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