Nonsteroidal anti-inflammatory drug

Definition

Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of medications that reduce inflammation, pain, and fever. They are commonly used to manage conditions such as arthritis, muscle pain, and other inflammatory disorders.

5 Must Know Facts For Your Next Test

1. NSAIDs inhibit the enzyme cyclooxygenase (COX), which plays a key role in the synthesis of prostaglandins involved in inflammation.
2. Common side effects of NSAIDs include gastrointestinal issues like ulcers and bleeding, making them risky for long-term use.
3. NSAIDs can interfere with kidney function and fluid balance, which is crucial to monitor in patients with compromised renal systems.
4. They may impact the respiratory system by potentially causing bronchospasm in individuals with asthma or chronic obstructive pulmonary disease (COPD).
5. Nutritional intake of certain foods like omega-3 fatty acids can naturally reduce inflammation and may complement or reduce the need for NSAID use.

Review Questions

• What is the primary mechanism through which NSAIDs reduce inflammation?
• List two common side effects associated with long-term NSAID use.
• How might NSAIDs affect patients with pre-existing respiratory conditions?

Related terms

Cyclooxygenase (COX): An enzyme responsible for the formation of pro-inflammatory chemicals called prostaglandins.

Prostaglandins: Lipid compounds that have diverse hormone-like effects, including promoting inflammation.

Omega-3 Fatty Acids: Essential fats found in fish and flaxseed that possess anti-inflammatory properties.