Zanamivir

Definition

Zanamivir is an antiviral medication used to treat and prevent influenza A and B. It works by inhibiting the enzyme neuraminidase, which is essential for the virus's replication.

5 Must Know Facts For Your Next Test

1. Zanamivir is administered via inhalation, often using a diskhaler device.
2. It is most effective when taken within 48 hours of the onset of flu symptoms.
3. Zanamivir can be used prophylactically to prevent influenza in exposed individuals.
4. Common side effects include cough, nasal congestion, and throat irritation.
5. It was one of the first neuraminidase inhibitors approved for clinical use.

Review Questions

• How does zanamivir inhibit influenza virus replication?
• What is the preferred method of administration for zanamivir?
• Within what time frame should zanamivir be administered to be most effective?

Related terms

Neuraminidase Inhibitor: A class of antiviral drugs that block the function of the viral neuraminidase protein, preventing viral replication.

Oseltamivir: An oral antiviral medication similar to zanamivir, also used to treat and prevent influenza A and B.

Influenza Virus: A contagious respiratory virus that causes seasonal flu epidemics with symptoms like fever, cough, and body aches.