Xenopus laevis

Definition

Xenopus laevis, commonly known as the African clawed frog, is a model organism frequently used in genetic engineering and developmental biology. Its oocytes are particularly valuable for studying gene expression and protein function.

5 Must Know Facts For Your Next Test

1. Xenopus laevis oocytes are large and easy to manipulate, making them ideal for microinjection experiments.
2. This species has been instrumental in studying RNA synthesis, translation, and splicing mechanisms.
3. The Xenopus genome has been sequenced, providing a valuable resource for genetic studies.
4. Xenopus embryos can be easily manipulated to study the effects of gene knockdowns or overexpression on development.
5. Researchers often use Xenopus laevis to produce recombinant proteins by injecting mRNA into oocytes.

Review Questions

• Why are Xenopus laevis oocytes advantageous for microinjection experiments?
• How has the sequencing of the Xenopus genome contributed to genetic studies?
• What techniques are commonly used with Xenopus embryos to study gene function?

Related terms

Microinjection: A technique that involves injecting substances directly into cells using a fine needle.

Model Organism: An organism that is extensively studied to understand particular biological phenomena.

RNA Splicing: The process by which introns are removed from pre-mRNA and exons are joined together.