Voriconazole

Definition

Voriconazole is an antifungal medication used to treat serious fungal infections, including those caused by Aspergillus and Candida species. It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes.

5 Must Know Facts For Your Next Test

1. Voriconazole is effective against a wide range of fungi, including molds and yeasts.
2. It is often used to treat invasive aspergillosis, especially in immunocompromised patients.
3. Common side effects include visual disturbances and liver enzyme abnormalities.
4. Voriconazole can interact with several other medications, requiring careful monitoring.
5. It is available in both oral and intravenous formulations for flexible administration.

Review Questions

• What types of fungal infections can voriconazole treat?
• What are common side effects associated with voriconazole?
• How does voriconazole inhibit fungal growth?

Related terms

Aspergillosis: A fungal infection caused by Aspergillus species that primarily affects the lungs.

Candida: A genus of yeast that can cause infections in various parts of the body, including the skin and mucous membranes.

Ergosterol: A sterol component of fungal cell membranes targeted by antifungal drugs like voriconazole.