Valganciclovir is an antiviral medication used primarily to treat cytomegalovirus (CMV) infections. It is a prodrug of ganciclovir with improved oral bioavailability.
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Valganciclovir is commonly prescribed for CMV infections, especially in immunocompromised patients such as organ transplant recipients and those with HIV/AIDS.
It works by inhibiting viral DNA synthesis, thus preventing the replication of the virus.
The drug is converted into its active form, ganciclovir, after ingestion and absorption in the gastrointestinal tract.
Due to its potent effects, valganciclovir can cause significant side effects including neutropenia, anemia, and thrombocytopenia.
Patients on valganciclovir require regular blood tests to monitor for potential toxicities and adjust dosing accordingly.
Review Questions
What type of infections is valganciclovir primarily used to treat?
How does valganciclovir inhibit viral replication?
Why are regular blood tests necessary for patients taking valganciclovir?