Microbiology

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Cytomegalovirus (CMV)

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Microbiology

Definition

Cytomegalovirus (CMV) is a common virus that can infect people of all ages and often remains dormant in the body. It is a member of the herpesvirus family and can cause severe complications in immunocompromised individuals and newborns.

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5 Must Know Facts For Your Next Test

  1. CMV is transmitted through bodily fluids such as saliva, blood, urine, semen, and breast milk.
  2. Primary CMV infection is often asymptomatic or causes mild flu-like symptoms in healthy individuals.
  3. In immunocompromised patients, such as those with HIV/AIDS or organ transplant recipients, CMV can lead to severe conditions like pneumonia, retinitis, or gastrointestinal disease.
  4. Congenital CMV infection occurs when a pregnant woman transmits the virus to her fetus, potentially resulting in serious birth defects or developmental disabilities.
  5. Diagnosis of CMV infection can be confirmed through serological tests that detect CMV-specific antibodies or molecular techniques like PCR to identify viral DNA.

Review Questions

  • What are the primary modes of transmission for cytomegalovirus?
  • Why is CMV particularly dangerous for immunocompromised individuals?
  • How can congenital CMV infection affect newborns?

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