Systemic mycoses

Definition

Systemic mycoses are fungal infections that affect internal organs and systems, often starting from the lungs and spreading to other parts of the body. These infections can become serious or life-threatening if not properly treated.

5 Must Know Facts For Your Next Test

1. Systemic mycoses are typically caused by inhalation of fungal spores.
2. Common fungi causing systemic mycoses include Histoplasma capsulatum, Coccidioides immitis, and Blastomyces dermatitidis.
3. Symptoms can range from mild respiratory issues to severe systemic involvement affecting multiple organs.
4. Diagnosis often involves imaging studies, serological tests, and tissue biopsies to identify the specific fungus.
5. Treatment usually requires prolonged antifungal therapy with medications such as amphotericin B and azoles.

Review Questions

• What are the primary modes of transmission for systemic mycoses?
• Which fungi are commonly responsible for causing systemic mycoses?
• What diagnostic methods are used to identify systemic mycoses?

Related terms

Histoplasmosis: A type of systemic mycosis caused by Histoplasma capsulatum.

Coccidioidomycosis: A systemic fungal infection caused by Coccidioides species.

Antifungal Therapy: Treatment involving drugs that inhibit or kill fungal pathogens.