Rabies virus (RV)

Definition

Rabies virus (RV) is a neurotropic virus that causes rabies, a deadly infection of the central nervous system. It is typically transmitted through the bite of an infected animal.

5 Must Know Facts For Your Next Test

1. The incubation period for rabies can vary from a few weeks to several months.
2. Rabies progresses through stages: prodromal, acute neurologic phase, and coma leading to death if untreated.
3. Negri bodies are cytoplasmic inclusions found in neurons infected with the rabies virus.
4. The primary means of transmission is through the saliva of infected animals via bites or scratches.
5. Post-exposure prophylaxis (PEP) is critical and effective if administered promptly after exposure.

Review Questions

• What are the stages of rabies progression?
• How is rabies primarily transmitted?
• What are Negri bodies and where are they found?

Related terms

Neurotropic virus: A virus that specifically targets nerve cells.

Post-exposure prophylaxis (PEP): Treatment administered after exposure to prevent infection.

Negri bodies: Cytoplasmic inclusions found in neurons infected with the rabies virus, used as a diagnostic indicator.