Phenolic compounds

Definition

Phenolic compounds are a class of chemical disinfectants that denature proteins and disrupt cell membranes, leading to microbial death. They are commonly used in healthcare settings for their broad-spectrum antimicrobial activity.

5 Must Know Facts For Your Next Test

1. Phenolic compounds are effective against a wide range of microorganisms, including bacteria, fungi, and viruses.
2. They can be used on surfaces, equipment, and skin but may cause irritation with prolonged exposure.
3. The effectiveness of phenolic compounds can be diminished in the presence of organic material such as blood or pus.
4. Common examples include triclosan and hexachlorophene, which have been used in antiseptic soaps and surgical scrubs.
5. Phenolics work by disrupting cell walls and precipitating cellular proteins, making them lethal to microbes.

Review Questions

• What types of microorganisms are phenolic compounds effective against?
• How do phenolic compounds disrupt microbial cells?
• Give two examples of commonly used phenolic compounds in healthcare settings.

Related terms

Disinfectant: A chemical agent used to destroy or inhibit the growth of harmful organisms.

Antiseptic: A substance that prevents infection by inhibiting the growth of infectious agents on living tissue.

Triclosan: An antibacterial and antifungal agent found in some consumer products, including disinfectants and antiseptic soaps.