Lymphogranuloma venereum

Definition

Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by certain serovars of Chlamydia trachomatis. It primarily affects the lymphatic system and is characterized by genital ulcers, swollen lymph nodes, and proctocolitis.

5 Must Know Facts For Your Next Test

1. LGV is caused by Chlamydia trachomatis serovars L1, L2, and L3.
2. It predominantly affects the lymphatic system leading to painful inguinal lymphadenopathy.
3. Initial symptoms include small painless genital or rectal lesions that often go unnoticed.
4. If untreated, LGV can lead to chronic complications such as strictures and fistulas in the anogenital region.
5. Diagnosis typically involves nucleic acid amplification tests (NAATs) on specimens from the affected area.

Review Questions

• Which serovars of Chlamydia trachomatis cause lymphogranuloma venereum?
• What are the primary systems and areas affected by LGV?
• What diagnostic method is commonly used to confirm LGV?

Related terms

Chlamydia trachomatis: A bacterium that causes various infections such as trachoma, urethritis, and LGV.

Nucleic Acid Amplification Tests (NAATs): A molecular technique used to detect specific genetic material from pathogens including bacteria like Chlamydia.

Proctocolitis: Inflammation of the rectum and colon often seen in advanced stages of LGV.