Lansoprazole

Definition

Lansoprazole is a proton pump inhibitor (PPI) that reduces stomach acid production. It is used to treat conditions like gastroesophageal reflux disease (GERD) and peptic ulcers caused by bacterial infections.

5 Must Know Facts For Your Next Test

1. Lansoprazole inhibits the H+/K+ ATPase enzyme in the stomach lining, reducing gastric acid secretion.
2. It is commonly prescribed for Helicobacter pylori eradication in combination with antibiotics.
3. Lansoprazole helps heal erosive esophagitis, which can be a result of chronic acid exposure due to infections like GERD.
4. Long-term use of lansoprazole may lead to vitamin B12 deficiency due to reduced stomach acid.
5. Overuse or misuse of lansoprazole can contribute to antibiotic resistance, particularly in treating H. pylori.

Review Questions

• How does lansoprazole reduce gastric acid production?
• What role does lansoprazole play in the treatment of Helicobacter pylori infections?
• What are potential long-term side effects of using lansoprazole?

Related terms

Helicobacter pylori:

A type of bacteria that causes infections in the stomach and is linked to ulcers.

Proton Pump Inhibitors (PPIs): A class of medications that reduce stomach acid production by inhibiting the H+/K+ ATPase enzyme.

Gastroesophageal Reflux Disease (GERD): A chronic digestive condition where stomach acid frequently flows back into the esophagus, causing irritation.