Itraconazole

Definition

Itraconazole is an antifungal medication used to treat a variety of fungal infections. It is particularly effective against dermatophytes, yeasts, and molds.

5 Must Know Facts For Your Next Test

1. Itraconazole works by inhibiting the enzyme lanosterol 14α-demethylase, which is crucial for fungal cell membrane synthesis.
2. It is commonly prescribed for mycoses of the skin such as tinea corporis (ringworm) and tinea pedis (athlete's foot).
3. For respiratory system infections, itraconazole is effective against aspergillosis and histoplasmosis.
4. Itraconazole can also be used to treat oral thrush and esophageal candidiasis in the digestive system.
5. The medication can interact with other drugs, so it is important to monitor for potential side effects like liver toxicity.

Review Questions

• What enzyme does itraconazole inhibit to exert its antifungal effects?
• Which types of mycoses can itraconazole be used to treat?
• What are some potential side effects or interactions associated with itraconazole?

Related terms

Fluconazole: Another antifungal medication often used to treat Candida infections.

Aspergillosis: A respiratory infection caused by Aspergillus species that can be treated with itraconazole.

Tinea Pedis: A common fungal infection of the feet also known as athlete's foot.