Hemorrhagic fever with renal syndrome

Definition

Hemorrhagic fever with renal syndrome (HFRS) is a group of illnesses caused by hantaviruses, characterized by fever, hemorrhage, and renal dysfunction. It primarily affects the vascular system and kidneys.

5 Must Know Facts For Your Next Test

1. HFRS is transmitted to humans through contact with rodent excreta or saliva.
2. The disease progresses through five distinct phases: febrile, hypotensive, oliguric, diuretic, and convalescent stages.
3. Symptoms include sudden onset of fever, headache, back pain, abdominal pain, nausea, and blurred vision.
4. Diagnosis is often confirmed through serological tests detecting hantavirus-specific antibodies.
5. There is no specific antiviral treatment for HFRS; management focuses on supportive care such as fluid management and dialysis if required.

Review Questions

• What are the primary modes of transmission for HFRS?
• List the five phases of hemorrhagic fever with renal syndrome.
• How is HFRS typically diagnosed in a clinical setting?

Related terms

Hantavirus Pulmonary Syndrome: A severe respiratory disease caused by hantaviruses leading to acute respiratory distress.

Rodent-borne viruses: Viruses that are transmitted to humans primarily through contact with rodent excreta or bites.

Renal Dysfunction: Impairment in kidney function which can lead to reduced urine output and accumulation of waste products in the body.