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Fertility factor

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Microbiology

Definition

The fertility factor (F factor) is a plasmid in bacteria that enables the transfer of genetic material through conjugation. It plays a crucial role in genetic diversity among prokaryotes.

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5 Must Know Facts For Your Next Test

  1. The F factor contains genes necessary for the formation of sex pili, which facilitate the transfer of DNA between bacterial cells.
  2. Bacteria possessing the F factor are termed F+ cells, while those lacking it are termed F- cells.
  3. During conjugation, an F+ cell can transfer a copy of its F factor to an F- cell, converting it into an F+ cell.
  4. The F factor can integrate into the bacterial chromosome, forming an Hfr (high-frequency recombination) strain, which can transfer chromosomal genes at high frequency during conjugation.
  5. Conjugation involving the F factor contributes to antibiotic resistance spread by allowing horizontal gene transfer.

Review Questions

  • What is the main function of the fertility factor in bacteria?
  • How does the presence of the fertility factor influence bacterial conjugation?
  • What distinguishes an Hfr strain from a regular F+ strain?

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