Diloxanide furoate

Definition

Diloxanide furoate is an antiprotozoal medication primarily used to treat infections caused by Entamoeba histolytica. It is effective against the luminal form of this amoeba and is typically used in combination with other medications.

5 Must Know Facts For Your Next Test

1. Diloxanide furoate is specifically used to treat asymptomatic cyst carriers of Entamoeba histolytica.
2. It is often administered orally in a dosage regimen lasting around 10 days.
3. The drug works by inhibiting protein synthesis in the protozoan, leading to its death.
4. Common side effects include nausea, flatulence, and abdominal cramps.
5. It is usually not recommended for use during pregnancy unless absolutely necessary.

Review Questions

• What type of protozoan infection is diloxanide furoate used to treat?
• Describe the mechanism of action of diloxanide furoate.
• What are some common side effects associated with diloxanide furoate?

Related terms

Entamoeba histolytica: A protozoan parasite responsible for causing amoebiasis.

Metronidazole: An antibiotic and antiprotozoal medication commonly used alongside diloxanide furoate.

Luminal agent: A type of drug that acts within the lumen of the intestines to eliminate pathogens.