Cytomegalovirus

Definition

Cytomegalovirus (CMV) is a common herpesvirus that can cause asymptomatic infections or severe disease in immunocompromised individuals. It particularly affects the gastrointestinal tract and can complicate organ transplants.

5 Must Know Facts For Your Next Test

1. CMV can be treated with antiviral drugs such as ganciclovir, valganciclovir, and foscarnet.
2. T lymphocytes play a crucial role in controlling CMV infections through cellular immunity.
3. Congenital CMV infection is one of the leading causes of hearing loss and developmental disabilities in children.
4. CMV can remain latent within the body and reactivate under conditions of immune suppression.
5. There is currently no licensed vaccine for CMV, but research is ongoing to develop one.

Review Questions

• Which antiviral drugs are commonly used to treat Cytomegalovirus (CMV) infections?
• How do T lymphocytes contribute to the control of CMV infections?
• What are some potential complications of congenital CMV infection?

Related terms

Antiviral Drugs: Medications used to treat viral infections by inhibiting the development of the virus.

Cellular Immunity:

Immune response that involves T lymphocytes attacking infected cells directly.

Congenital Infection: An infection present at birth, acquired from the mother during pregnancy.