Clotrimazole

Definition

Clotrimazole is an antifungal medication used to treat various fungal infections by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes. It is commonly applied topically for skin and mucous membrane infections.

5 Must Know Facts For Your Next Test

1. Clotrimazole works by disrupting the structure and function of the fungal cell membrane.
2. It is effective against dermatophytes, yeasts, and some molds.
3. Clotrimazole is often used to treat athlete's foot, jock itch, and ringworm.
4. It can also be used in the treatment of oral thrush and vaginal yeast infections.
5. Side effects are generally mild, including local irritation or burning sensation.

Review Questions

• How does clotrimazole disrupt fungal cells?
• Which types of infections can clotrimazole be used to treat?
• What are common side effects associated with clotrimazole?

Related terms

Ergosterol: A vital component of fungal cell membranes targeted by antifungal drugs like clotrimazole.

Dermatophytes: A type of fungus that causes skin infections such as athlete's foot and ringworm.

Oral Thrush: A fungal infection in the mouth caused by Candida species, often treated with clotrimazole.