Microbiology

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Charged tRNA

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Microbiology

Definition

Charged tRNA, also known as aminoacyl-tRNA, is a tRNA molecule that is covalently bonded to its corresponding amino acid. This charging process is essential for the addition of amino acids during protein synthesis.

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5 Must Know Facts For Your Next Test

  1. Charged tRNA is essential for translating mRNA codons into a specific amino acid sequence in proteins.
  2. The enzyme aminoacyl-tRNA synthetase catalyzes the attachment of an amino acid to its corresponding tRNA.
  3. Each type of tRNA has a specific anticodon that pairs with a complementary mRNA codon during translation.
  4. There are at least 20 different types of aminoacyl-tRNA synthetases, one for each amino acid.
  5. Incorrect charging of tRNAs can lead to errors in protein synthesis and potentially nonfunctional or harmful proteins.

Review Questions

  • What role does charged tRNA play in protein synthesis?
  • Which enzyme is responsible for attaching an amino acid to its corresponding tRNA?
  • How does the anticodon of charged tRNA relate to mRNA during translation?

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