Osmotic diuretics are a class of medications that promote diuresis by increasing the osmolarity of the blood and renal filtrate, leading to enhanced water excretion from the kidneys. These diuretics work primarily in the proximal convoluted tubule and the loop of Henle, where they draw water into the renal tubules, ultimately resulting in increased urine production. They are often used to manage conditions such as increased intracranial pressure and acute kidney injury.
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