CYP450 metabolism refers to a family of enzymes known as cytochrome P450s, which play a crucial role in the biotransformation of various compounds, including drugs, into more water-soluble metabolites for excretion. These enzymes are primarily found in the liver and are responsible for the oxidative metabolism of many immunosuppressants and immunomodulators, influencing their efficacy and safety. Understanding CYP450 metabolism is essential for predicting drug interactions and individual responses to medications in the context of immune modulation.
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