Double-strand breaks (DSBs) are a type of DNA damage where both strands of the DNA helix are severed, resulting in a complete disruption of the DNA molecule. This can occur due to various factors including exposure to radiation, chemicals, or during normal cellular processes such as replication. DSBs are particularly significant in the context of biological effects of radiation because they can lead to mutations, chromosomal rearrangements, and even cell death if not properly repaired.
congrats on reading the definition of double-strand breaks. now let's actually learn it.