Nociception

Definition

Nociception is the sensory process that provides signals that trigger pain. It involves the detection of harmful stimuli by nociceptors, which are specialized nerve endings.

5 Must Know Facts For Your Next Test

1. Nociceptors are found in skin, muscles, joints, and some internal organs.
2. The four main stages of nociception are transduction, transmission, modulation, and perception.
3. Nociceptive pain can be classified into somatic and visceral pain based on its origin.
4. Substances like bradykinin and prostaglandins can activate nociceptors.
5. The spinal cord plays a crucial role in transmitting nociceptive signals to the brain.

Review Questions

• What are the four main stages of nociception?
• Where are nociceptors located in the body?
• How do substances like bradykinin and prostaglandins contribute to nociception?

Related terms

Nociceptor: Specialized nerve endings that detect harmful stimuli and initiate the sensation of pain.

Somatosensation: The collective term for all sensory experiences arising from the skin, muscles, joints, and internal organs.

Prostaglandins: Lipid compounds that have hormone-like effects and play a key role in inflammation and activation of nociceptors.