Inhibin

Definition

Inhibin is a hormone produced by the gonads that inhibits the secretion of follicle-stimulating hormone (FSH) by the anterior pituitary gland. It plays a crucial role in the regulation of the reproductive system in both males and females.

5 Must Know Facts For Your Next Test

1. Inhibin is primarily produced by granulosa cells in females and Sertoli cells in males.
2. There are two types of inhibin: inhibin A and inhibin B, each with distinct roles in reproductive physiology.
3. In females, inhibin levels fluctuate during the menstrual cycle, peaking during the mid-luteal phase.
4. Inhibin B is more prominent in males and serves as an indicator of spermatogenesis.
5. High levels of inhibin can be used as a marker for certain ovarian tumors.

Review Questions

• What are the primary sources of inhibin in males and females?
• How do inhibin levels change throughout the female menstrual cycle?
• What is the significance of inhibin B levels in assessing male fertility?

Related terms

Follicle-Stimulating Hormone (FSH): A hormone secreted by the anterior pituitary gland that stimulates gamete production.

Granulosa Cells: Cells surrounding developing oocytes that produce estrogen and inhibin.

Sertoli Cells: Cells located within the seminiferous tubules of the testes that support sperm development and produce inhibin.