Creutzfeldt-Jakob disease (CJD) is a rare, degenerative neurological disorder caused by prions, which are misfolded proteins that induce abnormal folding of normal cellular proteins in the brain. This condition leads to rapid cognitive decline and severe neurological symptoms, ultimately resulting in death. CJD is one of the most well-known examples of prion diseases, highlighting the unique and dangerous nature of these acellular entities.
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