Podocytes

Definition

Podocytes are specialized cells in the kidneys that wrap around capillaries of the glomerulus, forming a crucial part of the filtration barrier that filters blood to form urine. They have foot-like extensions called foot processes or pedicels, which interlock with those of adjacent podocytes to prevent the passage of large molecules.

Related terms

Glomerulus: A network of tiny blood vessels located within the kidney where blood filtration begins.

Filtration barrier: A three-layered structure in the kidney comprising endothelial cells of glomerular capillaries, a basement membrane, and podocytes, working together to filter blood.

Nephron:

The functional unit of the kidney consisting of a glomerulus and its associated tubules, where blood filtration and urine formation occur