19.3 Implement Nutritional Strategies to Impact Musculoskeletal and Integumentary Wellness

4 min readjune 18, 2024

Calcium channel blockers are crucial medications for managing heart rhythm disorders. They work by blocking calcium entry into heart cells, slowing conduction and reducing contractility. This helps control rapid heart rates in conditions like atrial fibrillation and supraventricular tachycardia.

These drugs also dilate coronary arteries, improving blood flow to the heart. While effective for treating dysrhythmias, they can cause side effects like low blood pressure and slow heart rate. Proper monitoring and patient education are essential for safe and effective use of calcium channel blockers.

Calcium Channel Blockers for Dysrhythmias

Mechanisms of calcium channel blockers

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  • Block L-type calcium channels in cardiac muscle cells
    • Reduce calcium influx during depolarization, which is necessary for muscle contraction
    • Decrease intracellular calcium concentration, leading to reduced contractility (inotropy)
    • Disrupt excitation-contraction coupling, affecting the heart's ability to contract
  • Slow conduction through the AV node
    • Prolong AV nodal refractory period, preventing rapid impulse transmission
    • Decrease ventricular rate in atrial fibrillation and flutter (SVT)
  • Dilate coronary arteries
    • Improve coronary blood flow, increasing oxygen supply to the heart muscle (myocardium)
    • Reduce myocardial oxygen demand by decreasing cardiac workload
  • Decrease contractility and oxygen consumption
    • Reduce afterload (resistance against which the heart must pump) and preload (volume of blood in the ventricles at the end of diastole)
    • Beneficial in hypertrophic cardiomyopathy by reducing outflow tract obstruction and improving diastolic function

Effects of calcium channel blockers

  • Therapeutic uses
    • Supraventricular tachycardias (SVT)
      • Atrial fibrillation and flutter, characterized by rapid and irregular atrial contractions
      • AV nodal reentrant tachycardia (AVNRT), caused by a reentry circuit within the AV node
    • Angina pectoris, chest pain caused by insufficient blood flow to the heart muscle
    • Hypertrophic cardiomyopathy, a genetic disorder causing thickening of the heart muscle
  • Effects
    • Slow ventricular rate in SVT, improving cardiac function and reducing symptoms
    • Reduce myocardial oxygen demand, alleviating angina symptoms
    • Improve coronary blood flow, enhancing oxygen supply to the heart muscle
    • Decrease outflow tract obstruction in hypertrophic cardiomyopathy, improving cardiac output
    • Exert a negative inotropic effect, reducing the force of heart contractions
  • Potential side effects
    • Hypotension (low blood pressure) due to vasodilation and reduced contractility
    • Bradycardia (slow heart rate) and heart block (impaired conduction) due to AV node suppression
    • Peripheral edema (swelling) due to vasodilation and fluid retention
    • Constipation due to smooth muscle relaxation in the gastrointestinal tract
    • Dizziness and headache due to vasodilation and hypotension

Cardiac electrophysiology and calcium channel blockers

  • Voltage-gated ion channels play a crucial role in generating and propagating cardiac action potentials
  • Calcium channel blockers primarily affect the plateau phase of the cardiac action potential
  • These medications influence both chronotropic (heart rate) and inotropic (contractility) effects
  • Calcium channel blockers also act on vascular smooth muscle, leading to vasodilation and reduced peripheral resistance

Nursing considerations for administration

  • Assess baseline vital signs and cardiac rhythm to establish a reference point
  • Monitor blood pressure and heart rate closely
    • Report significant changes to the healthcare provider, as they may indicate the need for dose adjustment or intervention
  • Administer medication as prescribed
    • Use caution in patients with heart failure or conduction disorders, as they may be more sensitive to the effects of calcium channel blockers
  • Observe for signs of heart block or bradycardia
    • Prepare for temporary pacing if necessary, to maintain adequate heart rate and cardiac output
  • Educate patients on potential side effects and when to seek medical attention
  • Encourage medication adherence and regular follow-up appointments to ensure optimal treatment outcomes

Patient education for calcium channel blockers

  • Explain the purpose and mechanism of action of the prescribed calcium channel blocker
    • Use simple terms and analogies to help the patient understand how the medication works (slowing down the heart's electrical system)
  • Instruct the patient on proper dosage, timing, and administration of the medication
    • Emphasize the importance of taking the medication as directed to maintain consistent therapeutic levels
  • Discuss common side effects and how to manage them
    • Advise when to contact the healthcare provider for concerning symptoms (severe dizziness, fainting, or persistent edema)
  • Encourage lifestyle modifications to support heart health
    • Regular exercise (walking), stress management (meditation), and a heart-healthy diet (low in saturated fat and sodium)
  • Stress the importance of regular follow-up appointments and monitoring
    • Discuss the need for periodic blood tests and ECGs to assess the effectiveness and safety of the medication
  • Provide written materials and resources for additional information and support
    • Include contact information for the healthcare team and emergency services to ensure prompt assistance if needed

Key Terms to Review (32)

Arthritis: Arthritis is a general term for a group of conditions that cause inflammation and pain in the joints. It is a musculoskeletal disorder that can significantly impact an individual's mobility, flexibility, and overall quality of life. Understanding the role of nutrition in managing arthritis is crucial for implementing effective strategies to support musculoskeletal and integumentary wellness.
Bioavailability: Bioavailability refers to the degree and rate at which a substance, such as a nutrient or medication, is absorbed and becomes available for use or storage in the body. It is a crucial concept that connects the consumption of nutrients, minerals, and supplements to their ultimate impact on physiological processes and health outcomes.
Bone Mineral Density: Bone mineral density (BMD) refers to the amount of mineral matter per square centimeter of bones. It is a measure of the strength and health of an individual's bones, which is crucial for maintaining musculoskeletal and integumentary wellness, as well as managing various health conditions through appropriate nutritional treatments.
Client teaching: Client teaching involves educating patients about their health, wellness, and specific medical conditions. It aims to empower clients to make informed decisions about their nutrition and overall health.
Dermatitis: Dermatitis is a general term that refers to inflammation of the skin, characterized by redness, itching, and sometimes blistering or scaling. It is a common condition that can have various causes and manifestations, and it is closely linked to the health and functioning of the integumentary system.
DEXA Scan: A DEXA (Dual-Energy X-ray Absorptiometry) scan is a non-invasive imaging technique used to measure bone mineral density (BMD) and body composition, including fat mass and lean muscle mass. It plays a crucial role in assessing and analyzing the impact of nutrition on the musculoskeletal and integumentary systems, as well as in planning, implementing, and evaluating nutritional strategies to promote musculoskeletal and integumentary wellness.
Holistic assessment: Holistic assessment is a comprehensive evaluation that considers the physical, emotional, social, and spiritual aspects of a patient's well-being. It aims to understand the complete context of a patient's health to provide individualized care.
Holistic health: Holistic health is an approach to wellness that considers the whole person, including physical, emotional, social, and spiritual well-being. It emphasizes the interconnectedness of various aspects of health to achieve optimal wellness.
Hydration: Hydration refers to the process of maintaining adequate fluid levels within the body to support various physiological functions. It is a crucial aspect of overall health and wellness, with implications across multiple areas of nutrition and wellness.
Inflammation: Inflammation is the body's immune response to injury or harmful stimuli, characterized by redness, heat, swelling, and pain. It is a protective mechanism aimed at removing the injurious stimuli and initiating the healing process.
Insulin-like Growth Factor: Insulin-like growth factor (IGF) is a family of proteins that play a crucial role in regulating cell growth, differentiation, and metabolism. These growth factors are structurally and functionally similar to insulin, hence the name, and are essential for the development and maintenance of various tissues, including those in the musculoskeletal and integumentary systems.
Keratinocytes: Keratinocytes are the predominant cell type in the epidermis, the outermost layer of the skin. They are responsible for the production of keratin, a structural protein that provides strength and protection to the skin.
Mediterranean diet: The Mediterranean diet is a nutritional plan inspired by the traditional eating habits of countries bordering the Mediterranean Sea. It emphasizes whole foods, healthy fats, lean proteins, and abundant fruits and vegetables to promote overall health and well-being.
Mediterranean Diet: The Mediterranean diet is a plant-based eating pattern that emphasizes the consumption of whole, minimally processed foods commonly found in the countries surrounding the Mediterranean Sea. This diet is characterized by a high intake of fruits, vegetables, whole grains, legumes, nuts, and olive oil, along with moderate consumption of fish, poultry, and red wine. The Mediterranean diet has been extensively studied for its numerous health benefits, including its positive impact on evidence-based practice and nutrition, gut health, neurological wellness, endocrine wellness, hematological wellness, cardiovascular wellness, pulmonary wellness, and musculoskeletal and integumentary wellness.
Muscles: Muscles are tissues in the body composed of fibers that contract to produce movement and maintain posture. They play a crucial role in bodily functions, including locomotion and stability, especially important for nurses to understand in relation to nutrition and musculoskeletal health.
NSAIDS: NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) are a class of medications used to reduce inflammation, alleviate pain, and lower fevers. They are commonly used in managing conditions like arthritis and musculoskeletal injuries.
Nutrient Absorption: Nutrient absorption is the process by which the body takes in and utilizes the essential nutrients from the food we consume. It involves the complex mechanisms within the gastrointestinal system that facilitate the transport of macronutrients, micronutrients, and other compounds from the digestive tract into the bloodstream for distribution and use throughout the body.
Omega-3 Fatty Acids: Omega-3 fatty acids are a type of polyunsaturated fatty acid that are essential for human health. They play a crucial role in various bodily functions, including the maintenance of the neurological, endocrine, cardiovascular, and pulmonary systems. Omega-3s are considered 'essential' because the body cannot produce them on its own, and they must be obtained through diet or supplementation.
Osteoblasts: Osteoblasts are specialized cells responsible for the formation and mineralization of bone. They play a crucial role in the maintenance and repair of the musculoskeletal and integumentary systems by producing the organic matrix and regulating the deposition of calcium salts that harden the bone.
Osteoporosis: Osteoporosis is a chronic, progressive skeletal disorder characterized by a decrease in bone mass and deterioration of bone tissue, leading to an increased risk of fractures. This condition is closely linked to various aspects of nutrition, including protein, vitamins, minerals, and supplements, as well as its impact on the musculoskeletal and integumentary systems across the lifespan.
Parathyroid Hormone: Parathyroid hormone (PTH) is a polypeptide hormone produced by the parathyroid glands that plays a crucial role in regulating calcium and phosphate homeostasis in the body. It is a key player in maintaining the balance of these minerals, which is essential for the proper functioning of the renal, musculoskeletal, and integumentary systems.
Phytochemicals: Phytochemicals are a diverse group of naturally occurring plant-based compounds that have been shown to provide various health benefits beyond basic nutrition. These compounds are found in fruits, vegetables, grains, and other plant-based foods, and they play a crucial role in human health and wellness across multiple areas, including nutrition, supplements, cardiovascular health, and musculoskeletal and integumentary wellness.
Polyphenols: Polyphenols are naturally occurring compounds found in plants known for their antioxidant properties. They play a crucial role in protecting cells from oxidative stress and inflammation.
Protein Supplementation: Protein supplementation refers to the use of concentrated protein sources, such as powders, shakes, or bars, to increase an individual's overall protein intake beyond what can be obtained from a regular diet. This practice is often employed to support muscle growth, recovery, and overall musculoskeletal and integumentary wellness.
Psoriasis: Psoriasis is a chronic, autoimmune skin condition that causes the rapid buildup of skin cells, resulting in thick, scaly, and often inflamed patches on the skin. This term is particularly relevant in the context of understanding the impact of nutrition on the musculoskeletal and integumentary (skin) systems, as well as implementing and evaluating nutritional strategies to address musculoskeletal and integumentary wellness, and the role of nutrition in chronic musculoskeletal and integumentary illnesses.
Sarcopenia: Sarcopenia is the age-related loss of skeletal muscle mass and strength, leading to physical frailty and functional decline. This term is particularly relevant in the context of understanding the impact of nutrition on wellness across various aspects of health, including endocrine, pulmonary, musculoskeletal, and integumentary systems.
Serum Albumin: Serum albumin is a type of protein found in the blood plasma that plays a crucial role in maintaining fluid balance, transporting various molecules, and supporting overall health. It is the most abundant protein in the human body and is closely linked to several important physiological processes.
Skinfold Test: The skinfold test is a method used to assess body composition by measuring the thickness of subcutaneous fat at specific sites on the body. It provides an estimate of an individual's body fat percentage and is commonly used in the context of evaluating the musculoskeletal and integumentary systems.
Tendinitis: Tendinitis is the inflammation of a tendon, the tough, fibrous connective tissue that attaches muscle to bone. It is a common musculoskeletal condition that can cause pain, swelling, and impaired movement in the affected area.
Vitamin C Deficiency: Vitamin C deficiency is a condition characterized by a lack of ascorbic acid, an essential nutrient required for various bodily functions, including the maintenance of healthy musculoskeletal and integumentary systems.
Vitamin D: Vitamin D is a fat-soluble vitamin that plays a crucial role in maintaining overall health and wellness. It is often referred to as the 'sunshine vitamin' because the body can synthesize it when the skin is exposed to sunlight. Vitamin D is essential for the regulation of calcium and phosphorus levels in the body, supporting strong bones and teeth, and it also has important functions in various other physiological processes.
Zinc Deficiency: Zinc deficiency is a condition characterized by an inadequate amount of the essential mineral zinc in the body. Zinc is crucial for various physiological processes, including immune function, protein synthesis, wound healing, and the maintenance of healthy skin and hair.
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