Pharmacology for Nurses

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Xultrophy

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Pharmacology for Nurses

Definition

Xultrophy is a fixed-ratio combination drug containing insulin degludec and liraglutide, used to improve blood sugar control in adults with type 2 diabetes. It is administered via subcutaneous injection.

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5 Must Know Facts For Your Next Test

  1. Xultrophy combines insulin degludec (a long-acting basal insulin) with liraglutide (a GLP-1 receptor agonist).
  2. It helps lower blood glucose levels by both increasing insulin availability and reducing glucagon secretion.
  3. Common side effects include gastrointestinal issues like nausea and diarrhea, as well as potential hypoglycemia.
  4. Xultrophy is typically administered once daily at the same time each day, without regard to meals.
  5. It should not be used in patients with type 1 diabetes or diabetic ketoacidosis.

Review Questions

  • What are the two active components of Xultrophy, and what are their respective functions?
  • List three common side effects associated with Xultrophy.
  • Why is Xultrophy not suitable for patients with type 1 diabetes?

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