Very low-density lipoproteins (VLDL)

Definition

Very low-density lipoproteins (VLDL) are particles in the blood that carry triglycerides to tissues. They are produced by the liver and can contribute to the buildup of plaque in arteries.

5 Must Know Facts For Your Next Test

1. VLDL is primarily composed of triglycerides and small amounts of cholesterol.
2. The liver synthesizes VLDL, which then enters the bloodstream.
3. High levels of VLDL can lead to atherosclerosis, increasing the risk for cardiovascular diseases.
4. VLDL particles are converted into low-density lipoproteins (LDL) after delivering triglycerides to cells.
5. Medications such as statins and fibrates can help lower VLDL levels.

Review Questions

• What is the primary function of VLDL in the body?
• How does high VLDL contribute to cardiovascular disease?
• Which types of medications are commonly used to lower VLDL levels?

Related terms

Low-Density Lipoprotein (LDL): A type of lipoprotein that carries cholesterol to tissues and is often referred to as 'bad cholesterol'.

High-Density Lipoprotein (HDL): A type of lipoprotein that carries cholesterol away from tissues back to the liver, known as 'good cholesterol'.

Apolipoproteins: Proteins that bind lipids to form lipoproteins and transport them through the lymphatic and circulatory systems.