Pharmacology for Nurses

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Tramadol

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Pharmacology for Nurses

Definition

Tramadol is a synthetic opioid analgesic used to treat moderate to moderately severe pain. It functions by altering the way the brain and nervous system respond to pain.

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5 Must Know Facts For Your Next Test

  1. Tramadol is classified as a Schedule IV controlled substance under the Controlled Substances Act.
  2. It works by binding to mu-opioid receptors and inhibiting the reuptake of norepinephrine and serotonin, which contributes to its analgesic effects.
  3. Common side effects include dizziness, nausea, constipation, headache, and drowsiness.
  4. Tramadol has a risk of dependence and abuse, especially with prolonged use or at higher doses.
  5. It should not be used in combination with alcohol or other CNS depressants due to the increased risk of respiratory depression.

Review Questions

  • What mechanism does Tramadol use for its analgesic effects?
  • List three common side effects associated with Tramadol usage.
  • Why is Tramadol considered a Schedule IV controlled substance?

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