Probalan
from class: Pharmacology for Nurses Definition Probalan, also known as probenecid, is a medication used to decrease uric acid levels in the blood. It is commonly prescribed to treat gout and hyperuricemia.
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Predict what's on your test 5 Must Know Facts For Your Next Test Probalan works by inhibiting the reabsorption of uric acid in the kidneys, thereby increasing its excretion. It is often used in combination with other medications such as penicillin to enhance their effectiveness by slowing their excretion. Common side effects include nausea, headache, dizziness, and kidney stones. Patients with severe kidney disease should not use Probalan due to its mechanism of action being reliant on renal function. Probalan can interact with other drugs like aspirin, which can reduce its effectiveness. Review Questions What is the primary medical use of Probalan? How does Probalan affect uric acid levels in the blood? Why might Probalan be contraindicated in patients with severe kidney disease?
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