Plant alkaloids

Definition

Plant alkaloids are naturally occurring chemical compounds that contain basic nitrogen atoms, primarily derived from plants. They are often used in cancer therapy due to their ability to interfere with cell division.

5 Must Know Facts For Your Next Test

1. Plant alkaloids are commonly used as chemotherapeutic agents.
2. They work by inhibiting the mitotic spindle formation during cell division.
3. Examples include vincristine, vinblastine, and paclitaxel.
4. These drugs can cause side effects such as neuropathy and myelosuppression.
5. Plant alkaloids are often administered intravenously.

Review Questions

• What is the primary mechanism of action of plant alkaloids in cancer therapy?
• Name two examples of plant alkaloids used in chemotherapy.
• What are some common side effects associated with plant alkaloid chemotherapy?

Related terms

Chemotherapy: A type of cancer treatment that uses drugs to kill cancer cells.

Mitotic Spindle: A structure made of microtubules that segregates chromosomes during cell division.

Neuropathy: Damage or dysfunction of one or more nerves, typically causing numbness or weakness.