Pharmacology for Nurses

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Olanzapine

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Pharmacology for Nurses

Definition

Olanzapine is an atypical antipsychotic medication primarily used to treat schizophrenia and bipolar disorder. It works by altering the activity of certain natural substances in the brain.

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5 Must Know Facts For Your Next Test

  1. Olanzapine can cause significant weight gain and metabolic changes, including increased blood sugar and cholesterol levels.
  2. It is often administered orally but can also be given as an intramuscular injection for acute agitation.
  3. Common side effects include drowsiness, dizziness, dry mouth, constipation, and orthostatic hypotension.
  4. Olanzapine has a black box warning for increased mortality in elderly patients with dementia-related psychosis.
  5. The therapeutic effects of olanzapine may take several weeks to become fully apparent.

Review Questions

  • What are the primary uses of olanzapine?
  • What are some common side effects associated with olanzapine?
  • Why should olanzapine be used with caution in elderly patients?

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