Non-Hodgkin lymphoma

Definition

Non-Hodgkin lymphoma is a type of cancer that originates in the lymphatic system, specifically in the lymphocytes. It differs from Hodgkin lymphoma by the absence of Reed-Sternberg cells.

5 Must Know Facts For Your Next Test

1. Non-Hodgkin lymphoma is classified into B-cell and T-cell types, with B-cell being more common.
2. Risk factors include age, weakened immune system, certain infections, and exposure to chemicals like pesticides.
3. Symptoms often include swollen lymph nodes, fever, night sweats, and weight loss.
4. Treatment options vary based on the stage and type but may include chemotherapy, radiation therapy, targeted therapy, and immunotherapy.
5. Rituximab is a commonly used monoclonal antibody in the treatment of B-cell non-Hodgkin lymphoma.

Review Questions

• What are the two main classifications of non-Hodgkin lymphoma?
• List at least three common symptoms associated with non-Hodgkin lymphoma.
• Name a commonly used monoclonal antibody for treating B-cell non-Hodgkin lymphoma.

Related terms

Lymphatic System: A network of tissues and organs that help rid the body of toxins and waste.

Chemotherapy: A type of cancer treatment that uses drugs to kill rapidly dividing cells.

Immunotherapy:

A cancer treatment that helps your immune system fight cancer.