Lovenox

Definition

Lovenox is a brand name for enoxaparin, a low molecular weight heparin (LMWH) used as an anticoagulant to prevent and treat blood clots. It works by inhibiting factor Xa and thrombin in the coagulation cascade.

5 Must Know Facts For Your Next Test

1. Lovenox is commonly administered via subcutaneous injection.
2. It is used to prevent deep vein thrombosis (DVT) and pulmonary embolism (PE), especially after surgeries.
3. The dosage of Lovenox may need adjustment based on renal function as it is primarily excreted by the kidneys.
4. Patients on Lovenox should be monitored for signs of bleeding or bruising, which are common side effects.
5. Unlike unfractionated heparin, Lovenox does not require frequent monitoring of activated partial thromboplastin time (aPTT).

Review Questions

• What is the primary mechanism of action of Lovenox?
• Why might a patient's dosage of Lovenox need to be adjusted?
• What are common indications for prescribing Lovenox?

Related terms

Heparin:

A widely used anticoagulant that works by inhibiting several factors in the coagulation cascade.

Warfarin:

An oral anticoagulant that inhibits vitamin K-dependent clotting factors.

Thrombolytic Drugs:

Medications that dissolve blood clots by breaking down fibrin, used in acute treatment scenarios like myocardial infarction or stroke.