Indomethacin
from class: Pharmacology for Nurses Definition Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce inflammation and pain. It works by inhibiting the production of prostaglandins, which are chemicals in the body that cause inflammation.
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Predict what's on your test 5 Must Know Facts For Your Next Test Indomethacin is commonly prescribed for conditions like arthritis, gout, and bursitis. It inhibits cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, reducing prostaglandin synthesis. Common side effects include gastrointestinal issues such as ulcers and bleeding. Indomethacin can interact with other medications like anticoagulants, increasing the risk of bleeding. Patients with a history of heart disease or stroke should use indomethacin with caution due to potential cardiovascular risks. Review Questions What class of drugs does indomethacin belong to? How does indomethacin work to reduce inflammation? What are some common side effects associated with indomethacin?
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