Finasteride

Definition

Finasteride is a 5-alpha-reductase inhibitor used primarily to treat benign prostatic hyperplasia (BPH) and male pattern baldness. It works by preventing the conversion of testosterone to dihydrotestosterone (DHT).

5 Must Know Facts For Your Next Test

1. Finasteride is commonly prescribed in doses of 1 mg for hair loss and 5 mg for BPH.
2. It can take several months of consistent use before therapeutic effects are noticeable.
3. Side effects may include decreased libido, erectile dysfunction, and gynecomastia.
4. Pregnant women should avoid handling crushed or broken finasteride tablets due to potential risk to a male fetus.
5. It is metabolized in the liver and excreted via urine and feces.

Review Questions

• What are the primary medical uses of finasteride?
• How does finasteride work at the molecular level?
• What are some common side effects associated with finasteride?

Related terms

Alpha Blockers:

Medications that relax muscles in the prostate and bladder neck to improve urine flow.

Dihydrotestosterone (DHT):

A potent androgen hormone derived from testosterone that plays a role in male pattern baldness and BPH.

Benign Prostatic Hyperplasia (BPH): A non-cancerous enlargement of the prostate gland that can cause urinary symptoms.