Carbidopa/levodopa extended release

Definition

Carbidopa/levodopa extended release is a combination medication used to treat symptoms of Parkinson’s disease by replenishing dopamine. The extended-release formulation allows for a more consistent delivery of the medication over time.

5 Must Know Facts For Your Next Test

1. Levodopa is converted to dopamine in the brain, helping to manage motor symptoms.
2. Carbidopa prevents the breakdown of levodopa before it reaches the brain, increasing its effectiveness.
3. The extended-release form provides a more stable and prolonged effect compared to immediate-release formulations.
4. Common side effects include nausea, dizziness, and dyskinesia (involuntary movements).
5. Patients should not abruptly stop taking this medication as it can lead to severe withdrawal symptoms.

Review Questions

• What role does carbidopa play in the combination with levodopa?
• How does the extended-release formulation benefit patients with Parkinson’s disease?
• What are some common side effects associated with carbidopa/levodopa extended release?

Related terms

Dopamine:

A neurotransmitter involved in regulating movement and emotion.

Parkinson’s Disease: A neurodegenerative disorder characterized by motor symptoms such as tremors and rigidity.

Dyskinesia: Involuntary muscle movements that can occur as a side effect of long-term dopamine therapy.