Pharmacology for Nurses

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Captopril

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Pharmacology for Nurses

Definition

Captopril is an angiotensin-converting enzyme (ACE) inhibitor used primarily to treat high blood pressure and heart failure. It works by relaxing blood vessels, making it easier for the heart to pump blood.

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5 Must Know Facts For Your Next Test

  1. Captopril was the first ACE inhibitor approved for clinical use.
  2. Common side effects include cough, elevated potassium levels (hyperkalemia), and low blood pressure (hypotension).
  3. It can be used in diabetic patients to protect kidney function by reducing proteinuria.
  4. Captopril should not be used during pregnancy due to the risk of fetal harm.
  5. Regular monitoring of kidney function and electrolytes is essential during captopril therapy.

Review Questions

  • What is the primary therapeutic use of captopril?
  • Why should captopril not be used during pregnancy?
  • Which electrolyte imbalance is a common side effect of captopril?

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