Pharmacology for Nurses

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BiDil

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Pharmacology for Nurses

Definition

BiDil is a combination medication containing isosorbide dinitrate and hydralazine, used specifically to treat heart failure in self-identified Black patients. It works by dilating blood vessels to reduce the workload on the heart.

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5 Must Know Facts For Your Next Test

  1. BiDil was the first drug approved by the FDA for a specific racial group, particularly African Americans.
  2. It combines two active ingredients: isosorbide dinitrate, which relaxes blood vessels, and hydralazine, which lowers blood pressure.
  3. The primary indication for BiDil is to improve survival and reduce hospitalizations in heart failure patients.
  4. Patients taking BiDil may experience side effects such as headaches, dizziness, and hypotension.
  5. Clinical trials have shown that BiDil significantly reduces mortality rates in African American patients with heart failure.

Review Questions

  • What are the two active ingredients in BiDil and their respective roles?
  • Why was BiDil specifically approved for use in African American patients?
  • What are some common side effects associated with taking BiDil?

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