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Dehydration synthesis

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Organic Chemistry II

Definition

Dehydration synthesis is a chemical reaction in which two molecules are joined together by the removal of a water molecule. This process is crucial in forming larger organic molecules, such as proteins and polysaccharides, from smaller subunits. In the context of peptide bond formation, dehydration synthesis is essential for linking amino acids together, ultimately leading to the creation of proteins that perform vital functions within biological systems.

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5 Must Know Facts For Your Next Test

  1. Dehydration synthesis creates peptide bonds between amino acids, resulting in polypeptides and ultimately functional proteins.
  2. This reaction typically requires energy input to facilitate the formation of new covalent bonds during protein synthesis.
  3. During dehydration synthesis, the โ€“OH group from one amino acid and a hydrogen atom from another amino acid combine to form water, which is then released.
  4. Dehydration synthesis is not limited to proteins; it also plays a key role in forming carbohydrates and nucleic acids.
  5. The efficiency of dehydration synthesis reactions can be influenced by environmental factors such as temperature and pH.

Review Questions

  • How does dehydration synthesis contribute to the formation of proteins at a molecular level?
    • Dehydration synthesis contributes to protein formation by linking amino acids together through peptide bonds. In this process, the carboxyl group of one amino acid reacts with the amino group of another, releasing a molecule of water. This covalent bond formation not only creates polypeptides but also defines the primary structure of proteins, which is crucial for their subsequent folding and function.
  • Discuss the role of dehydration synthesis compared to hydrolysis in biological systems.
    • Dehydration synthesis and hydrolysis serve opposing functions in biological systems. While dehydration synthesis builds larger molecules like proteins and carbohydrates by removing water and forming covalent bonds, hydrolysis breaks these molecules down into smaller units by adding water. This balance between the two processes is vital for metabolism, allowing organisms to synthesize necessary macromolecules while also being able to degrade them for energy or recycling purposes.
  • Evaluate the importance of dehydration synthesis in the context of cellular processes and metabolism.
    • Dehydration synthesis is essential for cellular processes as it allows for the construction of complex macromolecules that are critical for life. The formation of proteins through this process provides cells with structural components and enzymes necessary for metabolic reactions. Additionally, the ability to synthesize polysaccharides from simpler sugars enables energy storage and structural integrity in cells. Overall, without dehydration synthesis, cellular functions would be severely hindered, impacting growth, repair, and energy management in living organisms.
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