Nucleophilic acyl substitution reaction

Definition

A nucleophilic acyl substitution reaction is a type of chemical reaction where a nucleophile replaces the leaving group in an acyl compound. This reaction is fundamental in organic chemistry for modifying carboxylic acid derivatives into other functional groups.

Related terms

Nucleophile:

A chemical species that donates an electron pair to an electrophile to form a chemical bond in a reaction.

Electrophile:

An electron-deficient atom or molecule that tends to accept an electron pair from a nucleophile.

Carboxylic Acid Derivatives:

Organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with another atom or functional group