Azide synthesis

Definition

Azide synthesis is a chemical process used to introduce azide groups (-N3) into molecules, often as a step towards creating amines. This method can involve various strategies, including substitution reactions where an azide ion replaces a leaving group in an organic compound.

Related terms

Nucleophilic substitution: A reaction where one nucleophile (e.g., azide ion) replaces another group or atom in a molecule.

Schmidt reaction: A chemical reaction involving the conversion of ketones or aldehydes to amines through the use of azides.

Curtius rearrangement:

A thermal decomposition of azides leading to isocyanates, which can further hydrolyze to form amines